Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
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Corrigendum: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
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متن کاملIntestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
Tetrahydrobiopterin (BH4) is a cofactor of a number of regulatory enzymes. Although there are no known BH4 exogenous sources, the tissue content of this biopterin increases with age in GTP cyclohydrolase 1-deficient hyperphenylalaninemia-1 (hph-1) mice. Since certain bacteria are known to generate BH4, we hypothesize that generation of this biopterin by the intestinal microbiota contributes to ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep39854